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(A) HT-1080, (B) MDA-MB-231, and HepG2 were incubated with the substrates in either serum-free (FBS(-)) or serum-containing (FBS(+)) media for 1 h. The data represent the means ± SD (n = 3). *: P < 0.05, ***: P < 0.005 vs. FBS(+).
