Table 2. Glucose metabolism disorders (GMD) among 454 study participants.
Variable | HIV-negative Control (n = 153) | HIV-infected ART-naïve (n = 151) | p-value vs. control | HIV-infected on ART (n = 150) | p-value vs. control |
---|---|---|---|---|---|
Proportion (%) Median (IQR) | Proportion (%) Median (IQR) | Proportion (%) Median (IQR) | |||
Any GMD * | 11 (7.2%) | 12 (8.0%) | 0.83 | 49 (32.7%) | <0.001 |
Diabetes mellitus | 8 (5.2%) | 1 (0.7%) | 0.04 | 27 (18.0%) | 0.001 |
Impaired fasting glucose | 0 | 5 (3.3%) | 0.03 | 1 (0.7%) | 0.50 |
Impaired glucose tolerance | 3 (2.0%) | 6 (4.0%) | 0.33 | 21 (14.0%) | <0.001 |
Fasting blood glucose (mmol/L) | 4.7 (4–5) | 4.7 (4–5.1) | 0.55 | 5.6 (4.8–6) | <0.0001 |
2-hour blood glucose (mmol/L) | 5.6 (5–6) | 5.5 (5–6.1) | 0.41 | 6.6 (5.8–8.1) | <0.0001 |
* Primary outcome: defined as either Diabetes Mellitus or Impaired Fasting Glucose or Impaired Glucose Tolerance