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Percentage absolute bias on Ki estimates, averaged over three ROIs, when noise level was set to (a) 0.5, (b) 2, (c) 4. Blue bars show the bias with the scaling method with one blood sample at the end of the study, green bars show the bias with the scaling method where the tail is fit to the multiple blood samples towards the end of study and red bars show the bias which would be present when all six parameters of the AIF was set to their true values.
