Table 3. Guanabenz Efficacy Study Survival Results Summary.

Age of ALS related death in 4.0 mg/kg qod efficacy study and 4.5 mg/kg/day efficacy study.

Study	Gender	Vehicle Treated Median Death Age (days)	Guanabenz Treated Median Death Age (days)	Trt—Veh (days)	P-value (Log-rank)
4.5 mg/kg/day Guanabenz	Male	121.5	117	-4.5	0.0266
4.5 mg/kg/day Guanabenz	Female	129.5	128	-1.5	0.8278
4.5 mg/kg/day Guanabenz	All	126	121	-5	0.3808
4 mg/kg qod Guanabenz	Male	128	116	-12	0.0149
4 mg/kg qod Guanabenz	Female	122.5	118	-4.5	0.0976
4 mg/kg qod Guanabenz	All	124	118	-6	0.0029