Table 2.

Study assessment schedules

Assessment	Baseline	At discharge	1 Week	4 Weeks	12 Weeks	26 Weeks	30 Weeks	52 Weeks
Consent and randomise	x
Contact details	x	f,e		a
Living circumstances	x	f		x	e	x		x
Training (physio, etc.)			e	e		e
10 Outcome-smRSq (mRS) [26, 31–33]	a			a		x		x
Depression diagnosis	x	f,e		a	x	x		x
PHQ2 [56]	f,e
PHQ9 [43]	a			a		a		a
MHI 5 [37–39]						f,e		f,e
MADRS [40, 41]					e	e		e
Emotionalism						e
DSM IV for depression [42]					e	e	e	e
SIS [34–36]						x		x
Fatigue subscale SF36 [44, 45]				x	e	x		x
Cognition (TICSm) [46]						a		a
Cognition (MoCA) [47]	e					e
EQ5D-5 L [48]			e	e		x		x
EQD thermometer						a		a
SF12 [59]								a
Adverse events		f,e	e	a,e	e	x		x
Adherence to IMP		f	e	a,e	e	x
All medications	x	f		a		x		a
Retrieve residual capsules (pill count)					e	x
Physical therapy received				e				e
Resource use over 12 months								x

f = FOCUS, a = AFFINITY, e = EFFECTS, x = completed in all three trials