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. 2015 Aug 21;13:274. doi: 10.1186/s12967-015-0638-2

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© Qi et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Frequency of Tregs generated in ACI recipients. a Representative dot plots of splenic Tregs. Percentages of CD4⁺CD25⁺Foxp3⁺ T cells are indicated in the top right corners of each dot plot. b Graphic results of frequency of splenic CD4⁺CD25⁺Foxp3⁺ T cells. Results are representative of five independent experiments. *p < 0.05 vs untreated; ^# p < 0.05 vs MSC. c Graphical representation of numbers of Foxp3⁺ T cells (cells/mm²) within the liver allografts. The results are representative of six separate experiments. *p < 0.05 vs untreated; ^# p < 0.05 vs MSC. d Representative immunohistochemistry staining of intragraft Foxp3⁺ T cells. (IHC, original magnification ×100)