Table 2.
Measures of disease activity for each year from 2004 to 2013 for patients with rheumatoid arthritis monitored with outcome measures in an ordinary outpatient clinic
| Year (patients) | ESR (mm/h) | CRP (mg/dl) | 28 tender joint count | 28 swollen joint count | DAS28-ESR | CDAI | SDAI | Assessor’s global assessment (VAS, mm) |
|---|---|---|---|---|---|---|---|---|
| 2004 | 22.3 (16.8) | 14.8 (18.9) | 4.2 (5.5) | 4.1 (4.6) | 3.9 (1.4) | 14.8 (10.9) | 16.2 (11.8) | 22.6 (16.1) |
| (n = 404) | [77.7 %] | [81.2 %] | [87.4 %] | [87.4 %] | [74.3 %] | [85.0 %] | [77.2 %] | [86.6 %] |
| 2005 | 22.1 (17.4) | 13.6 (15.2) | 4.0 (5.5) | 3.5 (4.1) | 3.8 (1.4) | 13.5 (10.6) | 14.7 (11.5) | 19.9 (15.3) |
| (n = 604) | [80.8 %] | [79.8 %] | [90.2 %] | [90.2 %] | [79.6 %] | [89.4 %] | [78.5 %] | [90.1 %] |
| 2006 | 22.7 (16.5) | 13.0 (13.1) | 4.8 (5.7) | 3.3 (3.7) | 4.0 (1.4) | 14.4 (10.4) | 15.5 (10.8) | 20.1 (16.1) |
| (n = 620) | [76.6 %] | [78.4 %] | [90.0 %] | [90.0 %] | [75.2 %] | [87.6 %] | [76.0 %] | [88.9 %] |
| 2007 | 23.3 (18.7) | 14.9 (18.0) | 4.5 (5.7) | 3.3 (4.0) | 3.9 (1.4) | 13.9 (11.0) | 15.7 (11.9) | 21.0 (16.3) |
| (n = 743) | [63.4 %] | [66.8 %] | [72.1 %] | [72.1 %] | [57.9 %] | [67.3 %] | [60.4 %] | [71.3 %] |
| 2008 | 20.9 (16.2) | 10.9 (17.4) | 3.6 (4.8) | 3.1 (3.7) | 3.6 (1.3) | 12.2 (10.0) | 13.3 (10.6) | 17.9 (15.9) |
| (n = 796) | [62.8 %] | [66.7 %] | [74.9 %] | [74.9 %] | [56.0 %] | [64.1 %] | [58.7 %] | [71.4 %] |
| 2009 | 19.4 (15.8) | 8.4 (14.2) | 2.9 (4.6) | 2.7 (3.6) | 3.3 (1.3) | 10.8 (9.4) | 11.9 (10.1) | 17.0 (16.0) |
| (n = 969) | [70.6 %] | [74.0 %] | [83.4 %] | [83.4 %] | [64.0 %] | [75.9 %] | [66.3 %] | [81.8 %] |
| 2010 | 19.1 (15.0) | 8.0 (12.6) | 2.5 (4.2) | 1.9 (3.1) | 3.2 (1.3) | 9.1 (8.3) | 9.8 (8.6) | 13.0 (12.7) |
| (n = 1069) | [80.4 %] | [81.2 %] | [89.9 %] | [89.9 %] | [77.4 %] | [85.4 %] | [77.6 %] | [88.5 %] |
| 2011 | 18.2 (14.7) | 7.1 (12.0) | 1.9 (3.4) | 1.4 (2.5) | 3.0 (1.2) | 8.0 (7.4) | 8.6 (7.7) | 12.9 (13.4) |
| (n = 1103) | [80.2 %] | [84.0 %] | [90.0 %] | [90.0 %] | [78.5 %] | [87.9 %] | [81.9 %] | [90.1 %] |
| 2012 | 18.0 (15.6) | 7.0 (13.2) | 1.5 (3.5) | 1.2 (2.5) | 2.8 (1.2) | 7.1 (7.1) | 7.8 (7.5) | 10.6 (12.6) |
| (n = 1113) | [78.0 %] | [83.1 %] | [91.3 %] | [91.3 %] | [75.8 %] | [88.2 %] | [80.6 %] | [91.0 %] |
| 2013 | 17.2 (14.2) | 6.4 (10.6) | 1.3 (3.0) | 0.8 (1.8) | 2.7 (1.1) | 6.3 (6.1) | 7.0 (6.3) | 9.7 (11.4) |
| (n = 1083) | [76.8 %] | [80.4 %] | [89.8 %] | [89.8 %] | [74.1 %] | [86.1 %] | [76.6 %] | [89.6 %] |
| P valuea 2004–2013 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 |
| P valuea 2010–2013 | 0.012 | 0.007 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 |
Abbreviations: CDAI: Clinical Disease Activity Index, CRP C-reactive protein, DAS28 Disease Activity Score in 28 joints, ESR Erythrocyte sedimentation rate, SDAI Simplified Disease Activity Index, VAS visual analogue scale, 0–100 mm
Data are mean (SD). The percentages within square brackets represent patients with available data
aLinear regression used to test for differences during follow-up