Table 3.
GO analysis of swine target genes. The table shows the GO annotation of the upregulated gene (A) and downregulated gene (B) in biological process, cellular component and molecular function. Ten GO terms for each process are listed
| GO.ID | Term | Count | P-value |
|---|---|---|---|
| Biological process | |||
| GO:0009987 | cellular process | 1782 | 1.0102E-05 |
| GO:0008152 | metabolic process | 1350 | 2.44953E-27 |
| GO:0065007 | biological regulation | 1260 | 0.000424577 |
| GO:0044238 | primary metabolic process | 1231 | 5.99319E-26 |
| GO:0044237 | cellular metabolic process | 1221 | 1.70495E-28 |
| GO:0050789 | regulation of biological process | 1192 | 0.002408788 |
| GO:0050794 | regulation of cellular process | 1147 | 0.000216533 |
| GO:0002376 | immune system process | 273 | 1.35305E-08 |
| GO:0006955 | immune response | 163 | 1.37682E-05 |
| GO:0000165 | MAPK cascade | 79 | 3.28195E-05 |
| Cellular Component | |||
| GO:0044464 | cell part | 1772 | 1.04304E-42 |
| GO:0005623 | cell | 1772 | 1.25735E-42 |
| GO:0005622 | intracellular | 1589 | 1.48695E-38 |
| GO:0044424 | intracellular part | 1512 | 9.75601E-38 |
| GO:0043226 | organelle | 1258 | 3.15768E-22 |
| GO:0043229 | intracellular organelle | 1255 | 5.59497E-22 |
| GO:0005737 | cytoplasm | 1146 | 1.88382E-25 |
| GO:0043227 | membrane-bounded organelle | 1131 | 3.1329E-23 |
| GO:0043231 | intracellular membrane-bounded organelle | 1129 | 3.31685E-23 |
| GO:0044444 | cytoplasmic part | 886 | 1.59538E-15 |
| Molecular Function | |||
| GO:0005488 | binding | 1781 | 7.2806E-35 |
| GO:0005515 | protein binding | 1406 | 1.01651E-30 |
| GO:0003824 | catalytic activity | 791 | 4.12422E-11 |
| GO:0043167 | ion binding | 425 | 2.86598E-07 |
| GO:0043169 | cation binding | 423 | 3.71961E-07 |
| GO:0046872 | metal ion binding | 416 | 4.07808E-07 |
| GO:0003676 | nucleic acid binding | 368 | 0.010086661 |
| GO:0036094 | small molecule binding | 366 | 1.33205E-09 |
| GO:0000166 | nucleotide binding | 341 | 4.24208E-09 |
| GO:0097159 | organic cyclic compound binding | 341 | 4.47117E-09 |
| B | |||
| Biological Process | |||
| GO:0009987 | cellular process | 1732 | 0.000468457 |
| GO:0008152 | metabolic process | 1280 | 0.000101041 |
| GO:0065007 | biological regulation | 1226 | 0.039474247 |
| GO:0044238 | primary metabolic process | 1179 | 0.011728824 |
| GO:0044237 | cellular metabolic process | 1153 | 0.011728824 |
| GO:0050789 | regulation of biological process | 1150 | 0.022891558 |
| GO:0050794 | regulation of cellular process | 1100 | 0.023393923 |
| GO:0002376 | immune system process | 265 | 3.49438E-08 |
| GO:0006955 | immune response | 161 | 7.5883E-06 |
| GO:0022402 | cell cycle process | 151 | 0.001985807 |
| Cellular Component | |||
| GO:0044464 | cell part | 1699 | 1.61069E-32 |
| GO:0005623 | cell | 1699 | 1.89406E-32 |
| GO:0005622 | intracellular | 1506 | 1.8551E-26 |
| GO:0044424 | intracellular part | 1426 | 4.89384E-25 |
| GO:0043226 | organelle | 1212 | 8.24637E-20 |
| GO:0043229 | intracellular organelle | 1208 | 2.30659E-19 |
| GO:0043227 | membrane-bounded organelle | 1089 | 8.12018E-21 |
| GO:0043231 | intracellular membrane-bounded organelle | 1088 | 5.50768E-21 |
| GO:0005737 | cytoplasm | 1079 | 5.97213E-18 |
| GO:0044444 | cytoplasmic part | 836 | 2.48602E-11 |
| Molecular Function | |||
| GO:0005488 | binding | 1748 | 3.63499E-36 |
| GO:0005515 | protein binding | 1408 | 1.06202E-38 |
| GO:0003824 | catalytic activity | 743 | 5.00132E-07 |
| GO:0043167 | ion binding | 410 | 2.18765E-06 |
| GO:0043169 | cation binding | 408 | 2.81762E-06 |
| GO:0046872 | metal ion binding | 400 | 4.31756E-06 |
| GO:0003676 | nucleic acid binding | 365 | 0.004482893 |
| GO:0036094 | small molecule binding | 335 | 6.20944E-06 |
| GO:0000166 | nucleotide binding | 309 | 2.81002E-05 |
| GO:0097159 | organic cyclic compound binding | 309 | 2.91504E-05 |