Fig 1. The Presence of the Minor Allele in the ADRAβ2 rs1042717 Gene When Interacted with Increasing Sexual Scores is Protective Against an IBS Diagnosis.

ADRAβ2 rs1042717 (A/G or A/A) in the presence of an elevated ETI-SR sexual abuse score results in a lower likelihood of IBS (interaction term OR = 0.73, 95% CI: 0.55–0.98, p = 0.039). Odds ratios and 95% CIs for a unit increase in ETI-SR sexual abuse score are reported from separate logistic regression models run within each genetic subgroup.