Table 4. Prevalence of Catecholaminergic Genotypes in IBS Patients and Healthy Controls.
SNP (Gene) | Healthy Controls | IBS Patients | ||||||
---|---|---|---|---|---|---|---|---|
rs1556832 (ADRA1D) | C/C | C/T | T/T | No Call | C/C | C/T | T/T | No Call |
166 (43.6%) | 159 (41.7%) | 51 (13.4%) | 5 (1.3%) | 93 (33.5%) | 134 (48.2%) | 47 (16.9%) | 4 (1.4%) | |
rs946188 (ADRA1D) | A/A | A/G | G/G | No Call | A/A | A/G | G/G | No Call |
191 (50.1%) | 162 (42.5%) | 20 (5.2%) | 8 (2.1%) | 140 (50.4%) | 118 (42.4%) | 11 (4%) | 9 (3.2%) | |
rs1432622 (ADRAβ2) | C/C | C/T | T/T | No Call | C/C | C/T | T/T | No Call |
164 (43%) | 161 (42.3%) | 50 (13.1%) | 6 (1.6%) | 106 (38.1%) | 128 (46%) | 40 (14.4%) | 4 (1.4%) | |
rs2400707 (ADRAβ2) | G/G | A/G | A/A | No Call | G/G | A/G | A/A | No Call |
164 (43%) | 161 (42.3%) | 51 (13.4%) | 5 (1.3%) | 106 (38.1%) | 129 (46.4%) | 41 (14.7%) | 2 (0.7%) | |
rs1042717 (ADRAβ2) | G/G | A/G | A/A | No Call | G/G | A/G | A/A | No Call |
164 (43%) | 161 (42.3%) | 51 (13.4%) | 5 (1.3%) | 106 (38.1%) | 129 (46.4%) | 41 (14.7%) | 2 (0.7%) | |
rs1042713 (ADRAβ2) | G/G | A/G | A/A | No Call | G/G | A/G | A/A | No Call |
120 (31.5%) | 165 (43.3%) | 84 (22%) | 12 (3.1%) | 95 (34.2%) | 123 (44.2%) | 47 (16.9%) | 13 (4.7%) | |
rs1800497 (ANKK1) | C/C | C/T | T/T | No Call | C/C | C/T | T/T | No Call |
192 (50.4%) | 148 (38.8%) | 36 (9.4%) | 5 (1.3%) | 159 (57.2%) | 93 (33.5%) | 24 (8.6%) | 2 (0.7%) | |
rs6269 (COMT) | A/A | A/G | G/G | No Call | A/A | A/G | G/G | No Call |
171 (44.9%) | 158 (41.5%) | 46 (12.1%) | 6 (1.6%) | 107 (38.5%) | 129 (46.4%) | 38 (13.7%) | 4 (1.4%) | |
rs4680 (COMT) | G/G | A/G | A/A | No Call | G/G | A/G | A/A | No Call |
128 (33.6%) | 181 (47.5%) | 68 (17.8%) | 4 (1%) | 98 (35.3%) | 111 (39.9%) | 59 (21.2%) | 10 (3.6%) | |
rs174697 (COMT) | G/G | A/G | A/A | No Call | G/G | A/G | A/A | No Call |
250 (65.6%) | 107 (28.1%) | 19 (5%) | 5 (1.3%) | 219 (78.8%) | 52 (18.7%) | 6 (2.2%) | 1 (0.4%) | |
rs6280 (DRD3) | T/T | C/T | C/C | No Call | T/T | C/T | C/C | No Call |
142 (37.3%) | 169 (44.4%) | 66 (17.3%) | 4 (1%) | 107 (38.5%) | 123 (44.2%) | 44 (15.8%) | 4 (1.4%) |