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. Author manuscript; available in PMC: 2015 Aug 22.
Published in final edited form as: Integr Biol (Camb). 2015 Jul 6;7(7):815–824. doi: 10.1039/c5ib00105f

Fig. 5.

Fig. 5

COMSOL simulation of HGF secretion, diffusion and convection in the microchambers. (A) One group of stimulated hepatocytes secreting HGF. (B) 20 islands containing hepatocytes secreting HGF. Note adjacent chamber is assumed to be free of cells in this model. (C) A scenario where source and recipient hepatocytes are secreting HGF. Source hepatocytes reside on top of HGF spots and become stimulated to produce HGF at 3 times the rate of recipient cells. Secretion rates and other parameters relevant to modeling are described in Table 2.