Table 1. Baseline characteristics of the patients.
| Variable | HDF(n = 358) | HD(n = 356) |
|---|---|---|
| Age (year) | 64.1±14.0 | 64.0±13.4 |
| Male sex—no. (%) | 214 (60) | 231 (65) |
| Region | ||
| Netherlands-no. (%) | 300 (84) | 297 (83) |
| Canada- no. (%) | 51 (14) | 51(14) |
| Norway- no. (%) | 7 (2) | 8 (2) |
| History of cardiovascular disease—no. (%) | 151 (42) | 162 (46) |
| Diabetes mellitus—no. (%) | 92 (26) | 78 (22) |
| Body mass index after dialysis—kg/m2 | 25.2±5.0 | 25.6±4.6 |
| Dialysis vintage (year) | ||
| -Median (inter-quartile range) | 1.8 (1.0–3.7) | 2.1 (1.0–4.0) |
| Systolic blood pressure—mmHg | 147±21 | 148±22 |
| Diastolic blood pressure-mmHg | 75±12 | 76±12 |
| Vascular access | ||
| Arteriovenous fistula- no. (%) | 279 (78) | 288 (81) |
| Graft- no. (%) | 57 (16) | 43 (12) |
| Central catheter- no. (%) | 22 (6) | 25 (7) |
| Number of treatments/week | ||
| -3- no. (%) | 332 (93) | 338 (95) |
| -2- no. (%) | 26 (7) | 18 (5) |
| Duration of a dialysis session—min | 226±26 | 227±22 |
| Blood flow—mL/min | 302±39 | 299±41 |
| Dialysis single pool Kt/Vurea | 1.41±0.24. | 1.38±0.19 |
| Residual kidney function no.(%)* | 186 (52) | 190 (53) |
| Estimated glomerular filtration rate | ||
| -ml/min/1.73m2; median (inter-quartile range) | 0.32 (0–3.30) | 0.30 (0–3.35) |
| Hemoglobin—mmol/L | 7.4±0.82 | 7.3±0.73 |
| Phosphorus—mmol/L | 1.65±0.51 | 1.63±0.47 |
| Beta-2-microglobulin—mg/L | 30.7±14.3 | 32.3±13.6 |
| Albumin—g/L^ | 40.2±3.8 | 40.6±3.9 |
| Creatinine–μmol/L pre-dialysis | 842±260 | 879±250 |
Values are means ±SD, median (interquartile range) or number (percentage).
HDF = online hemodiafiltration; HD = hemodialysis;
~pre-dialysis
*residual kidney function if diuresis >100 ml/24h
^albumin concentrations measured with the bromcresolpurple method have been converted to the bromcresolgreen method
To convert hemoglobin in mmol/L to g/dL divide by 0.62; phosphorus in mmol/L to mg/dL, divide by 0.323; albumin in g/L to g/dL, divide by 10; creatinine in μmol/L to mg/dL divide by 88.4