Table 5.

Cyclic mechanical stretch affects secretion of MMP-2 in VSMCs in vitro

Study	Cell type	Freq.	Unit	Stretch	Plate	Axis	Time	Wave	Results
Seo [67]	AoSMC (rat)	1 Hz	FX-4000	0–10 %	Pronectin		0–12 h		MMP-2 ↑
Yamashita [68]	AoSMC (rat)	0.5 Hz	STREX	2 %, 5 %, 20 %	Laminin	Uniaxial	48 h		MMP-2 ↑
Grote [69]	AoSMC (mouse)	0.5 Hz	FX-3000	15 %	Collagen I		0–24 h		MMP-2 ↑