Table 2.

Long-term exacerbation rate. Long-term (months 3–12) exacerbation rate in all patients, based on cut-points of ≥2, ≥6, and ≥10 reliever inhalations/day in the week preceding the 2-month visit

Mean reliever use (inhalations/day)	Exacerbation ratea or ratio	95 % CI	P-value
<2	0.596	(0.470, 0.756)
2–5	0.724	(0.594, 0.882)
6–9	0.996	(0.806, 1.230)
≥10	1.403	(1.115, 1.766)
2–5 versus <2	1.214	(0.891, 1.654)	0.22
6–9 versus <2	1.670	(1.215, 2.296)	0.0016
≥10 versus <2	2.353	(1.687, 3.282)	<0.001

CI confidence interval

^aRates are normalized for 10 months and expressed as events per year. Analysis adjusted for treatment effects