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. 2015 Aug 20;10(8):e0135925. doi: 10.1371/journal.pone.0135925

Fig 1. Measurements of inner and outer layer thicknesses using optical coherence tomography C-scan in eyes with an indiopathic macular hole.

Fig 1

(A) Layer-by-layer measurements of the retina in a healthy eye. Thicknesses in the whole (ILM-RPE), inner (ILM-IPL [A], ILM-NFL [B], and GCL-IPL [C]), and outer (ONL-RPE [D]) layers measured on the basis of each colored line showing the border of automatically segmented layers. The PROS length [E] at the fovea and at a distance of 1.5 mm away from the fovea manually evaluated using B-scan. ILM: internal limiting membrane, RPE: retinal pigment epithelium, IPL: inner plexiform layer, NFL: nerve fiber layer, GCL: ganglion cell layer, ONL: outer nuclear layer, PROS: photoreceptor outer segment. (B-D) Overall retinal thicknesses (B) and the thicknesses of the inner 4 sectors (C) and outer 4 sectors (D) defined as the mean of the map sector values circled in red. (E) PROS length manually measured using vertical and horizontal scans through the central fovea at 5 spots: the fovea and the parafoveal sites (superior, inferior, nasal, and temporal) at a distance of 1.5 mm from the fovea. Representative case (Case 3) showing PROS length at the fovea and the temporal and nasal spots, pre-operatively and at 1 and 6 months post-surgery.