Table 1. Summary of properties of 27 novel P. falciparum proteins.
| Clone | RAS Sera | IFA SPZ | IFA LS | IFA BS | SPZ localization | Ex vivo | Cultured |
|---|---|---|---|---|---|---|---|
| Blot | ELISpot | ELISpot | |||||
| Pre-erythrocytic (Sporozoites or Sporozoites/Liver Stages) | |||||||
| Pf01 | + | + | + | - | NT | NT | + |
| Pf24 | + | + | NT | - | Cytoplasm | NT | + |
| Pf26 | + | + | + | - | NT | + | NT |
| Pf47 | + | + | NT | - | NT | NT | NT |
| Pf72 | + | + | NT | - | NT | NT | + |
| Pf77 | + | + | - | - | NT | NT | + |
| Pf83 | + | + | NT | - | NT | NT | + |
| Pf116 | + | + | + | - | Surface | + | NT |
| Sporozoites, Liver Stages, and Blood Stages | |||||||
| Pf02 | + | + | + | + | Surface membranes | - | NT |
| Pf08 | + | + | + | + | Surface | - | + |
| Pf09 | + | + | + | + | NT | + | NT |
| Pf13 | + | + | + | + | Surface, interior | NT | + |
| Pf43 | + | + | NT | + | NT | NT | NT |
| Pf56 | + | + | + | + | Surface clumps, cytoplasm | + | NT |
| Pf61 | + | + | + | + | Cytoplasm | + | NT |
| Pf78 | - | + | + | + | Inner pellicular membrane | - | + |
| Pf84 | + | + | + | + | Surface clumps | + | NT |
| Pf106 | + | + | + | + | Interior vesicles | + | NT |
| Pf119 | + | + | + | + | Nucleus | - | - |
| Pf121 | + | + | + | + | Interior vesicles | + | NT |
| Pf144 | + | + | + | + | Micronemes, ER | + | NT |
| Localization Not Determined | |||||||
| Pf49 | + | ND | ND | ND | ND | NT | NT |
| Pf51 | + | ND | ND | ND | ND | NT | + |
| Pf59 | + | ND | ND | ND | ND | NT | NT |
| Pf68 | + | ND | ND | ND | ND | NT | NT |
| Pf93 | + | ND | ND | ND | ND | - | + |
| Pf131 | + | ND | ND | ND | ND | NT | + |
RAS = irradiated sporozoites; Blot = Western Blot; + = positive; - = negative; ER = Endoplasmic Reticulum; SPZ = Sporozoite; LS = Liver Stage; BS = Blood Stage; NT = Not Tested; ND = Not Determined (proteins were not sufficiently immunogenic to induce antibody responses).