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. 2015 Aug 20;10(8):e0136167. doi: 10.1371/journal.pone.0136167

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Fig 6 — (A) Activity. Flies were fed food containing 50 mM caffeine and their activity monitored with the same procedure as methamphetamine treatment. Control flies showed an increased activity in the presence of caffeine, whereas flies expressing DN-Rab10 in all neurons showed no increase. Two-way ANOVA: F (1, 74) = 7.32, p < 0.01 for caffeine and F (1,74) = 1.87, p > 0.058 for genotype. Sidak's multiple comparisons test: *p < 0.05, t = 2.309 for control flies and p > 0.05, t = 0.103 for flies expressing DN-Rab10 in all neurons. (B) Mortality. The mean survival time was 33 hours for control flies and 28 hours for flies expressing DN-Rab10 in all neurons (Appl>DN-Rab10).