Table 3.

Path analysis for direct analgesic effect on the reduction of the BPI average pain score

Week	Direct effect	Indirect effect
Week 2a	84.3	15.7
Week 4a	83.8	16.2
Week 6a	63.1	36.9
Week 10a	43.2	56.8
Week 14a	41.6	58.4
Endpointb	28.3	71.7

Values are the percentages of direct and indirect effects

^aObserved case

^bLast observation carried forward