Table 3.
Univariate Cox regression modeling for the overall survival using each of the clinical parameters (A) and multivariate Cox regression modeling by combining four variables (P <0.05 in univariate analysis) (B) in validation set I. All the variables (except the metastasis site) were considered as continuous values
| A. Univariate analysis of validation set I | |||
|---|---|---|---|
| Concordance index | P value (Likelihood ratio test) | P value (Logrank test) | |
| Wang_4genescore | 0.81 | 0.0006 | 7×10−05 |
| Hemoglobin | 0.75 | 0.001 | 0.001 |
| VisceralMetastasis | 0.58 | 0.006 | 1×10−05 |
| LDH | 0.72 | 0.043 | 0.016 |
| BoneMetastasis | 0.56 | 0.051 | 0.15 |
| EosinophilCount | 0.69 | 0.052 | 0.068 |
| PSA | 0.62 | 0.12 | 0.066 |
| AP | 0.61 | 0.18 | 0.13 |
| NLRatio | 0.57 | 0.18 | 0.14 |
| MonocyteCount | 0.46 | 0.19 | 0.11 |
| PlateletCount | 0.62 | 0.3 | 0.3 |
| NeutrophilCount | 0.50 | 0.4 | 0.4 |
| Gleason | 0.52 | 0.7 | 0.7 |
| LymphocyteCount | 0.59 | 0.7 | 0.7 |
| BasophilCount | 0.48 | >0.9 | >0.9 |
| B. Multivariate analysis of validation set I | |||
| P value (Wald’s test) | |||
| Wang_4genescore | 0.045 | ||
| Hemoglobin | 0.18 | ||
| visceralMets | 0.13 | ||
| LDH | 0.4 | ||