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. 2015 Aug 20;9(8):e0004021. doi: 10.1371/journal.pntd.0004021

Fig 3. Reactivity of Schistosoma mansoni recombinant antigens in the multiplex immunoassay.

Fig 3

Multiplex assays were performed using samples from S. mansoni (Mbita) and S. haematobium (Kwale) endemic areas, respectively. Negative control samples from each location were included as comparator for the diagnostic efficacy of each antigen for the two species of schistosomes. The bar lines represent the median while the error bars represent the interquartile range. Antigens used in this assay: (A) Filamin; (B) GAPDH; (C) GST; (D) LAP-1; (E) LAP-2; (F) RP26; (G) Sm-SERPIN; (H) Sm31; (I) Sm32; (J) Tropomyosin-2; (K) SEA. Statistical significance was set at p < 0.05 as depicted using asterisks: * = p < 0.05, ** = p < 0.01, *** = p < 0.001, and **** = p < 0.0001. Jpn: healthy Japanese (n = 7), Sm-: egg negative in Sm endemic area (n = 26), Sm+: S. mansoni egg positive (n = 26), Sh-: egg negative in Sh endemic area (n = 26), Sh+: S. haematobium egg positive (n = 26).