Fig 7. Inhibition of miR27a causes a reduction of drug resistance genes in OCUM-2MD3/L-OHP cells.

OCUM-2MD3/L-OHP cells were transfected with Anti-miR27a (A), the expression levels of MDR1/P-gp, LRP, Bcl-, GST-π and TS were detected by RT-qPCR (B) and Western blotting (C, D). β-actin was used for an endogenous reference to standardize the protein expression levels. Results were presented as the mean ± S.D. (n = 3). *P<0.01 compared with non-targeted siRNA group.