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. 2015 Aug 20;11(8):e1005446. doi: 10.1371/journal.pgen.1005446

Fig 7. The constitutively active mig-2(gm103) gain-of-function allele displays unc-5 mutant-like phase 2 D/V migration failures suppressed by over-expressing unc-5(+) in the DTCs.

Fig 7

(A-C) DIC images of posterior gonad arms in L4 stage hermaphrodites. In mig-2(gm103) the anterior or posterior (shown) DTC or both (C), like unc-5(e53) (B), fails to execute the phase 2 D/V migratory phase and generates ventralized gonad arms. (D) Phase 2 failures of mig-2(gm103) are significantly suppressed by evIs129, which over-expresses unc-5 in the DTCs. The corresponding raw data, including the data for the anterior DTC, are presented in S6 Table. Error bars indicate the standard error of the sample proportion. Comparisons of phase2 D/V migration failures were made between paired mig-2(gm103) and mig-2(gm103) evIs129 doubles. ***P <0.00001; **P<0.001; *P<0.01.