Table 1. Overview of the demographic data.
| All HF-rTMS treated patients (26 patients) | Active HF-rTMS session (13 patients) | Sham HF-rTMS session (13 patients) | P-value | |
|---|---|---|---|---|
| Gender (Male/Female) | 17/9 | 9/4 | 8/5 | ≥0.99 |
| Age (year) | Total: M = 45.2, SD = 9.3 | M = 46.7, SD = 10.4 | M = 43.7, SD = 8.1 | 0.42 |
| Men: M = 45.1, SD = 10.5 | ||||
| Women: M = 45.4,SD = 6.9 | ||||
| Stimulation depth (mm) | M = 20.5, SD = 2.5 | M = 20.3, SD = 2.8 | M = 20.6, SD = 2.4 | 0.77 |
| Benzodiazepine free days before stimulation | M = 14.3, SD = 5.6 | M = 14.3, SD = 5.6 | M = 10.2, SD = 3.2 | 0.03 |
| % nicotine | 76.9% (20 patients) | 11 patients | 9 patients | ≥0.99 |
| % comorbid drug dependence | 15.4% (4 patients) | 3 patients (2 patients: cocaine; 1 patient cannabis) | 1 patient (cannabis) | 0.59 |
| % comorbid benzodiazepine dependence | 7.7% (2 patients) | 1 patient | 1 patient | 1.00 |
| Use of anti-craving medication before stimulation (washout of 2 weeks) | 2 patients | 1 patient | 1 patient | 1.00 |
| Baseline Alcohol Urge Questionnaire (AUQ) | M = 15.9, SD = 11.0 | M = 17.8, SD = 11.4 | M = 14.2, SD = 10.8 | 0.47 |
| Baseline 5-item Obsessive Compulsive Drinking Scale (OCDS) | M = 3.8, SD = 3.8 | M = 4.5, SD = 3.7 | M = 3.2, SD = 4.0 | 0.27 |
| Number of days patients drank more than 5 units/day (during the last month before hospitalization) (Alcohol Severity Index (ASI)) | M = 19.6, SD = 9.6 | M = 16.9, SD = 11.2 | M = 22.5, SD = 6.8 | 0.17 |
| Duration of alcohol addiction (years) (ASI) | M = 12.1, SD = 9.9 | M = 13.7, SD = 11.4 | M = 10.3, SD = 8.1 | 0.41 |
| Days between last alcohol intake and the start of the stimulation | M = 17.8, SD = 6.0 | M = 19.0, SD = 4.5 | M = 16.5, SD = 7.2 | 0.31 |
Demographic data concerns the entire patient group. Therefore, the two patients who were not presented with the block-related cue-exposure were also considered. MT: motor threshold; M: mean; SD: standard deviation.