Fig 3. Images obtained in a 72-year-old man clinicoradiologically considered as having tumor progression.

Contrast-enhanced, T1-weighted image (A) acquired 14 weeks after concomitant chemoradiotherapy (CCRT) shows a rim-enhancing lesion in the right hemisphere. DSC perfusion MR image (B) shows signal loss in the corresponding area possibly caused by treatment-related hemorrhage. The corresponding contrast-enhancing solid tumor portion shows intermediate to low ADC value (C) as well as increased permeability on the DCE perfusion MR image (D). Contrast-enhanced, T1-weighted image (E) acquired 22 weeks after CCRT shows the contrast-enhancing lesion is more enlarged, suggesting tumor progression.