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. 2015 Mar 29;6(16):14153–14164. doi: 10.18632/oncotarget.3686

Figure 1. Expression of miR-221/222 in pancreatic cancer tissues and cell lines.

Figure 1

(A) miR-221/222 were detected in 21 pancreatic cancer patients by qRT-PCR. The data are presented for those genes with a >1.5-fold increase in pancreatic cancer tissues relative to non-tumor adjacent tissues. (B) The relative expression of miR-221/222 in pancreatic cancer cell lines (Bxpc-3, Miapaca-2, Panc-1 and SW-1990) was detected by qRT-PCR. (C) The miR-221/222 mimics or inhibitors transfection efficiency was confirmed by qRT-PCR. The results showed that the levels of miR-221/222 in transformed Panc-1 cells increased by 4.15 ± 0.46/4.16 ± 0.57-fold or were reduced by 0.38 ± 0.05/0.39 ± 0.06-fold following transfection with miR-221/222 mimics or miR-221/222 inhibitors, respectively. U6 shRNA was used as an internal control. Data are expressed as the mean ± SD for three separate experiments performed in duplicate (*p < 0.05).