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. 2015 May 5;6(16):14300–14317. doi: 10.18632/oncotarget.3883

Figure 5. Fibroblasts induce cancer cell invasion in 2D and 3D conditions.

Figure 5

A. Representative images of SW620-GFP invasion from spheroids cultured for 4 days alone or on a fibroblast-DsRED layer (2D condition). B. Quantification of SW620 invasion of experiment in panel A, represented as mean +/− SD. C. Image of SW620-GFP invading the fibroblast layer out of a spheroid. D. Quantification of SW620-GFP spheroid invasion after 4 days under indicated conditions represented as mean +/− SD. E. Representative images of SW620-GFP 3D spheroids in presence or absence of fibroblasts-DsRED after 4 days. Arrows are indicating invasion areas.