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. 2015 May 4;6(16):14497–14506. doi: 10.18632/oncotarget.3988

Figure 5. The working model depicting the role of the NSL complex in c-Jun activated gene expression.

Figure 5

c-Jun recruits the NSL complex to its target genes upon activation. The NSL complex catalyzes H4K16 acetylation to promote c-Jun target gene transcription and promotes the release of the repressive NuRD complex from the c-Jun target genes, thus activating c-Jun.