Skip to main content
. Author manuscript; available in PMC: 2016 Sep 1.
Published in final edited form as: Appl Microbiol Biotechnol. 2015 Jul 29;99(18):7465–7479. doi: 10.1007/s00253-015-6821-9

Figure 4.

Figure 4

Chemical synthesis, depolymerization and enzymatic depolymerization of ultra-low molecular weight heparin and low molecular weight heparin. A. Summary of a convergent multi-step chemical synthesis of Arixtra from cellobiose derivative (reagents not shown). B. Enzymatic (I) and chemical (III) depolymerization to prepare low molecular heparins from unfractionated heparin (II).