Table 1. Meta-analysis of 3q29 deletion and schizophrenia.

Ref.	Ethnicity	Selection of controls	SZ cases	Case 3q29 del	Controls	Control 3q29 del	CMH OR (95% CI, P-value) with this sample removed
Levinson et al.³	European American	EM	2667	4	2648	0	36.4 (4.7 –1799.3, 8.4e−07)
Levinson et al.³	African American	EM	1273	1	963	0	40.2 (5.4–1924.3, 1.0e−07)
Szatkiewicz et al.⁴	Swedish	EM	4129	5	5478	0	33.4 (4.2–1695.3, 3.4e−06)
Rees et al.⁶	Mixed (95% European ancestry)	EM	6882	4	11 255	0	33.3 (4.2–1691.5, 2.6e−06)
Mulle et al.⁹	Ashkenazi Jewish	EM	554	1	1014	0	39.0 (5.2–1882.6, 1.6e−07)
Walsh et al.¹⁰	Mixed (78% Caucasian)	EM	150	1	256	0	39.1 (5.3–1887.4, 1.5e−07)
Rudd et al.¹¹	No information (recruited from Iowa)	No information (recruited from Iowa)	166	0	52	0	41.1 (5.6–1953.6, 5.8e−08)
Derks et al.¹²	Scottish (ID with SZ)	Scottish (ID w/o SZ)	64	0	66	0	41.1 (5.6–1953.6, 5.8e−08)
Ahn et al.¹³	COS: ‘highly heterogeneous'	Unaffected sibs of cases	126	0	69	0	41.1 (5.6–1953.6, 5.8e−08)
Priebe et al.¹⁴	German	EM	1637	0	1627	0	41.1 (5.6–1953.6, 5.8e−08)
Van Den Bossche et al.¹⁵	Belgian, Swedish, Scottish	EM	1259	2	1173	0	38.9 (5.2–1881.2, 2.1e−07)
Buizer-Voskamp et al.¹⁶	Dutch	EM	834	1	672	0	40.1 (5.4–1922.3, 1.0e−07)
Stefansson et al.¹⁷	Northern European/European	EM	1438	0	33,246	1	∞ (6.7–∞, 2.7e−08)
Magri et al.¹⁸	Italian	EM	172	1	160	0	40.0 (5.4–1917.5, 1.1e−07)
Xu et al.¹⁹	Afrikaner SZ trios (de novo CNV)	Afrikaner control trios (de novo CNV)	152	0	156	0	41.1 (5.6–1953.6, 5.8e−08)
International Schizophrenia Consortium²⁰	Mixed European	EM	3391	2	3181	0	38.9 (5.2–1880.7, 2.1e−07)
Costain et al.²¹	European ancestry	EM	420	0	416	0	41.1 (5.6–1953.6, 5.8e−08)
Total			25 314	22	62 432	1
Raw OR			54.3 (95% CI: 8.8–2215.7, P-value 2.2e−11)
CMH OR			41.1 (95% CI: 5.6–1953.6, P-value 5.8e−08)

Abbreviations: CI, confidence interval; CNV, copy number variation; CMH, Cochran–Mantel–Haenszel; COS, childhood-onset schizophrenia; EM, ethnically matched; ID, intellectual disability; OR, odds ratio; SZ, schizophrenia.