Table 5. Comparison between the synthesis rates of the proteins and the corresponding mRNAs of E. coli exposed to CYA or OLA.
Protein name | Gene name | Fold change mRNA (Protein) | |||
---|---|---|---|---|---|
0.5×MIC CYA | MBC CYA | MIC OLA | MBC OLA | ||
FumA | fumA | -1.10 | -1.38 | 1.93 | 1.40 (<-2) |
MreB | mreB | 1.11 (Absent) a | 1.33 | 1.20 | 1.46 |
SelB | selB | 1.01 | 1.20 | 1.13 | 1.30 (<-2) |
EftU1 | tuf | 1.02 (Absent) | 1.00 (<-2) b | 1.01 (<-2) | 1.08 |
KpsU | kpsU | -1.23 | -1.10 | -1.18 | -1.03 (<-2) |
Ssb | ssb | 1.46 | 1.86 (Appear) c | 1.56 | 1.74 (>2) d |
YfbU | yfbU | 1.07 (<-2) | 1.05 | 1.22 (<-2) | 1.35 |
CH60 | groL | 1.30 | 1.59 | 1.32 | 1.94 (Absent) |
YgfZ | ygfZ | 1.05 | 1.09 | -1.09 | 1.12 (Appear) |
RpoC | rpoC | 1.25 (Absent) | 1.28 | 1.40 | 1.57 |
Odp1 | aceE | 1.00 (<-2) | 1.11 | 1.42 | 1.23 |
PflB | pflB | 1.04 (Absent) | -1.04 | -1.10 | 1.08 |
NanE | nanE | -1.23 | -1.11 | -1.07 (Absent) | -1.08 |
IadA | iadA | -1.02 | 1.02 | -1.06 (<-2) | -1.09 |
NarY | narY | 1.07 | 1.12 (Appear) | -1.01 | 1.12 |
Dps | dps | 1.25 (>2) | 1.38 | 1.74 | 2.13 |
FolD | folD | 1.01 (Appear) | 1.01 | 1.15 | 1.18 |
NuoC/D | nuoC | -1.04 (Appear) | -1.04(Appear) | 1.06 | -1.09 |
LexA | lexA | 4.07 | 4.54 (Absent) | 4.30 | 4.68(< -2) |
a Absent represents proteins that only appear in control group.
b <-2 represents proteins that are down-regulated more than 2-fold with statistical significance (P<0.01).
c Appear represents proteins that only appear in drug-treated groups.
d >2 represents proteins that are up-regulated more than 2-fold with statistical significance (P<0.01).