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. 2015 Aug 21;11(8):e1005120. doi: 10.1371/journal.ppat.1005120

Fig 3. Inflammatory phenotypes of germ-free HBZ-Tg mice.

Fig 3

(A) GF HBZ-Tg mice developed dermatitis similarly to SPF HBZ-Tg mice. (B) Splenocytes were harvested from 18-week-old GF HBZ-Tg or GF WT littermates. The percentages of Tregs and effector/memory CD4+ T cells were evaluated. Representative results of the dot plots and a summarized table are shown. (C) Cytokine production in CD4+ T cells was evaluated. Splenocytes were stimulated with PMA/ionomycin in the presence of protein transport inhibitor for 4 hours, stained with specific antibodies, and analyzed by flow cytometry. Representative results of the dot plots and a summarized table are shown.