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. 2015 Aug 21;10(8):e0136245. doi: 10.1371/journal.pone.0136245

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© 2015 Yang et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Fig 2 — A,B: brain MRI scan of the proband at the age of 42; C-F: brain MRI scan of the proband at the age of 44; G,H: brain MRI scan of the patient Ⅳ20 at the age of 46. Atrophy of whole brain was present in both patients. The frontotemporal atrophy was the most noticeable, while in the proband the hippocampus was relatively well-preserved.