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. 2015 Aug 21;10(8):e0136242. doi: 10.1371/journal.pone.0136242

Table 1. Selected properties of synthetic compounds.

compound R-isomer S-isomer
[α]D (°) a) rt (min) b) ee (%) b) [α]D (°) a) rt (min) b) ee (%) b)
CCG-1423 +107 43.7 c) >99.9 –103 31.2 c) >99.9
CCG-100602 –78 8.8 d) 98.8 +79 5.4 d) 99.0
CCG-203971 –88 11.3 e) 99.0 +89 16.7 e) 99.1

a) Measured in methanol; c 1; temperature: 27°C (CCG-1423), 25°C (CCG-100602 and CCG-203971).

b) Determined by HPLC, column: 4.6Φ × 250 mm; eluent: n-hexane/ethanol; flow rate: 1 ml/min; temperature: 30°C; detection: UV254 nm.

c) CHIRALPAK AD, n-hexane/ethanol = 200/3.

d) CHIRALPAK AD, n-hexane/ethanol = 85/15.

e) CHIRALPAK OD, n-hexane/ethanol = 85/15.