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Comparison of VEGF-C/D, CEA, and CA19-9 in predicting the presence of GBC
| Parameters | Sensitivity | Specificity | PPVa | NPVb | Accuracy |
|---|---|---|---|---|---|
| VEGF-C | 71.0 % | 80.0 % | 84.6 % | 64.0 % | 74.5 % |
| VEGF-D | 74.2 % | 85.0 % | 88.5 % | 68.0 % | 78.4 % |
| VEGF-C + D | 80.6 % | 65.0 % | 78.1 % | 68.4 % | 74.5 % |
| CEA | 41.9 % | 95.0 % | 92.9 % | 51.4 % | 62.8 % |
| CA19-9 | 54.8 % | 90.0 % | 89.5 % | 56.3 % | 68.6 % |
| CEA + CA19-9 | 64.5 % | 85.0 % | 87.0 % | 60.7 % | 74.0 % |
aPositive predictive value
bNegative predictive value
