Table 3.

Multivariate linear regression model of variables significantly associated with total and free testosterone levels as well as testosterone-to-estradiol ratio (ratio T/E₂) as dependent variables

Variable	β	SE (β)	95 % CI	P value
Total testosterone
Obesity	−0.153	0.194	−0.546; 0.240	0.435
DM2	−0.617	0.220	−1.061; −0.173	0.008
Age	−0.171	0.118	−0.410; 0.068	0.157
Triglycerides	−0.054	0.106	−0.269; 0.160	0.610
HOMA-IR	−0.015	0.168	−0.354; 0.324	0.929
SAT cell size	−0.324	0.153	−0.633; −0.015	0.040
Free testosterone
Obesity	0.049	0.218	−0.391; 0.489	0.822
DM2	−0.239	0.246	−0.735; 0.258	0.337
Age	−0.472	0.132	−0.740; −0.205	0.001
Triglycerides	0.043	0.119	−0.197; 0.282	0.722
HOMA-IR	−0.077	0.188	−0.457; 0.302	0.683
SAT cell size	−0.446	0.171	−0.791; −0.100	0.013
Ratio T/E 2
Obesity	−0.183	0.274	−0.772; 0.357	0.455
DM2	−0.519	0.323	−1.271; 0.061	0.073
Age	0.089	0.211	−0.325; 0.543	0.610
Triglycerides	−0.158	0.143	−0.437; 0.153	0.330
HOMA-IR	0.116	0.302	−0.493; 0.750	0.673
SAT cell size	−0.391	0.218	−0.897; 0.002	0.051
SAT aromatase	−0.167	0.184	−0.565; 0.192	0.319

Significant P values were indicated in bold

All β coefficients were standardized. N = 50

Obesity and DM2 are binary variables (yes/no). DM2 type 2 diabetes, HOMA-IR homeostasis model of assessment for insulin resistance, SAT subcutaneous adipose tissue, SE standard error, CI confidence interval