Table 2. Multivariate and Univariate Analyses of Factors Independently Associated With Compensated Cirrhosis With Liver Biopsy a.
| Variables | Univariate Analysis | Multivariate Analysis | ||||
|---|---|---|---|---|---|---|
| Coefficient | OR, 95% CI | P Value | Coefficient | OR, 95% CI | P Value | |
| Gender (male) | 0.138 | 1.148 (0.534 - 2.468) | 0.723 | 0.123 | 1.131 (0.296 - 4.328) | 0.857 |
| Age, y | 0.029 | 1.029 (1.001 - 1.057) | 0.039 | 0.004 | 1.003 (0.960 - 1.050) | 0.868 |
| HBsAg, log 10 IU/mL | -2.358 | 0.095 (0.045 - 0.200) | < 0.001 | -2.300 | 0.100 (0.037 - 0.272) | < 0.001 |
| ALT, U/L | -0.001 | 0.998 (0.996 - 1.001) | 0.140 | -0.001 | 0.999 (0.996 - 1.002) | 0.481 |
| AST, U/L | 0.330 | 1.391 (1.083 - 1.788) | 0.010 | 0.003 | 1.012 (1.001 - 1.061) | 0.414 |
| HBV DNA, log 10 IU/mL | -0.237 | 0.789 (0.633 - 0.983) | 0.035 | -0.043 | 0.897 (0.609 - 1.127) | 0.862 |
| PLT, × T9/L a | -0.008 | 0.992 (0.984 - 0.999) | < 0.001 | -0.028 | 0.973 (0.959 - 0.986) | < 0.001 |
| Albumin, g/L | -0.187 | 0.861 (0.800 - 0.921) | < 0.001 | -0.012 | 0.938 (0.894 - 0.990) | 0.011 |
a Abbreviations: 95% CI, 95% confidence interval; ALT, alanine aminotransferase; AST, aspartate aminotransferase; HBsAg, hepatitis B surface antigen; HBV, hepatitis B virus; OR, odds ratio; and PLT, platelet.