Table 3. Sensitivity, Specificity and Predictive Values of Different HBsAg Levels for Predicting Compensated Cirrhosis a.
HBsAg, IU/mL | Number of Patients | Sensitivity b | Specificity b | PPV b | NPV b | LR+ | LR- |
---|---|---|---|---|---|---|---|
< 4000, 3.60 Log 10 | 74 | 80.3 | 82.4 | 66.2 | 90.7 | 4.56 | 0.22 |
< 3000, 3.48 Log 10 | 60 | 67.2 | 86.6 | 68.3 | 86.1 | 5.02 | 0.38 |
< 2000, 3.30 Log 10 | 38 | 42.6 | 91.5 | 68.4 | 78.8 | 5.04 | 0.63 |
< 1000, 3.00 Log 10 | 18 | 21.3 | 96.4 | 72.2 | 74.1 | 6.05 | 0.82 |
< 500, 2.70 Log 10 | 9 | 14.8 | 100 | 100 | 73.2 | - | 0.85 |
a Abbreviations: HBsAg, hepatitis B surface antigen; LR+, positive likelihood rate; LR-, negative likelihood rate; NPV, negative predictive value; and PPV, positive predictive value.
b Values’ unit is %.