Table 1.
Baseline Demographic and Clinical Characteristics
| Characteristics | Overall n=31 |
Treatment Assignment | P Value | |
|---|---|---|---|---|
| Placebo n=16 |
Oxytocin n=15 |
|||
| Demographics | ||||
| Age (yrs) | 42.6 ± 9.2 | 43.7 ± 7.6 | 41.4 ± 10.7 | 0.652 |
| Male % (n) | 83.9 (26) | 93.7 (15) | 73.3 (11) | 0.172 |
| Caucasian % (n) | 16.1 (5) | 18.8 (3) | 13.3 (2) | 0.999 |
| Smoke Cigs % (n) | 71.0 (22) | 68.8 (11) | 73.3 (11) | 0.999 |
| ACE Score | 1.68 ± 1.42 | 1.63 ± 1.15 | 1.73 ± 1.71 | 0.887 |
| Clinical Measures | ||||
| DHEA (ng/ml) | 2.33 ± 1.14 | 2.13 ± 0.70 | 2.57 ± 1.48 | 0.789 |
| Cortisol (ng/ml) | 0.20 ± 0.14 | 0.17 ± 0.08 | 0.23 ± 0.18 | 0.494 |
| Use Characteristics | ||||
| Currently Enrolled in Tx | 3.2 (1) | 6.3 (1) | 0.0 (0) | -- |
| Past Enrolled in Tx | 38.7 (12) | 37.5 (6) | 40.0 (6) | 0.886 |
| Age at First Use | 24.7 ± 6.8 | 24.7 ± 5.8 | 24.7 ± 8.0 | 0.638 |
| Age at Dependence | 29.2 ± 8.7 | 28.6 ± 7.5 | 29.7 ± 10.0 | 0.984 |
| Total Years of Use | 16.1 ± 8.1 | 16.1 ± 7.6 | 16.1 ± 8.9 | 0.969 |
| Using Days per Month | 16.2 ± 6.5 | 17.0 ± 7.4 | 15.3 ± 5.3 | 0.782 |
| Days abstinent | 10.6 ±12.0 | 11.8 ± 15.3 | 9.5 ± 8.0 | 0.592 |
| $ per Using Day | 75.6 ± 53.7 | 87.2 ± 68.1 | 63.2 ± 30.0 | 0.468 |
Note. Standard descriptive statistics were used to summarize the general demographic and clinical data. Cortisol and DHEA means and standard deviations are untransformed scores. Group differences in continuous characteristics were assessed using a Wilcoxon Rank-Sum test and differences in categorical characteristics were assessed using normal (Pearson’s) chi-square tests (Fisher’s Exact test used when appropriate).