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. Author manuscript; available in PMC: 2016 Sep 1.
Published in final edited form as: J Immunol. 2015 Jul 29;195(5):1939–1943. doi: 10.4049/jimmunol.1500969

Figure 1. cGAS is required for lethal autoimmune disease in Trex1-deficient mice.

Figure 1

Survival curves of cGAS+/+Trex1−/− (n=33), cGAS+/−Trex1−/− (n=44), and cGAS−/−Trex1−/− (n=29) mice. Both cGAS-deficient and Trex1-deficient mice were on a pure C57BL/6 background. Statistical analysis was performed with a Log-rank (Mantel-Cox) test. *p < 0.0001.