Table 4.

Cohen’s d effect size for behaviors

A. Time in Proximity to Stimulus Animal
	Cohen’s d effect size	Percentile standing	Overlap (%)
Females
DMSO	1.0	84	62
EB	1.6	95	42
A1221 (0.5)	0.8	79	69
A1221 (1)	0.3	62	88
Males
DMSO	0.7	76	73
EB	1.3	90	52
A1221 (0.5)	0.5	69	80
A1221 (1)	0.9	82	65

B. Time Investigating Stimulus Animal
	Cohen’s d effect size	Percentile standing	Overlap (%)
Females
DMSO	0.7	76	73
EB	0.7	76	73
A1221 (0.5)	0.5	69	80
A1221 (1)	0.2	58	92
Males
DMSO	0.2	58	92
EB	1.2	88	55
A1221 (0.5)	0.6	73	76
A1221 (1)	0.5	69	80

C. Time Spent Nose Touching
	Cohen’s d effect size	Percentile standing	Overlap (%)
Females
DMSO	1.4	92	48
EB	0.5	69	80
A1221 (0.5)	0.4	66	84
A1221 (1)	0.5	69	80
Males
DMSO	0.9	82	65
EB	0.8	79	69
A1221 (0.5)	0.5	69	80
A1221 (1)	1.0	84	62

Cohen’s d effect size was calculated for time spent in proximity to, investigating, and nose touching with, the familiar vs. the novel stimulus animal, in the Social Novelty test. An effect size of 0.8 or higher (in bold) is equivalent to Cohen’s standard LARGE, which indicates that the mean of the control group (Familiar) is at the 79th percentile and sharing 69% overlap with the comparison group (Novel).