Table 3.
Genotypes | Control | POP |
Crude P value, OR (95% CI) |
Adjusted P valueaOR, (95% CI) | ||
---|---|---|---|---|---|---|
Number (%) n = 291 |
HWP | Number (%) n = 210 |
HWP | |||
rs12237222 | ||||||
T/T | 104 (35.7) | 0.63 | 55 (26.2) | 0.21 | 0.023 (dom) 1.57 (1.06–2.31) |
0.12 (dom) 1.41 (0.91–2.18) |
T/G | 136 (46.7) | 114 (54.3) | ||||
G/G | 51 (17.5) | 41 (19.5) |
HWP: Hardy-Weinberg probability; OR: odds ratio; CI: confidence interval; dom: dominant model.
aAdjusted by age, body mass index (BMI), perineal trauma in childbirth, and vaginal parity. In multivariate analysis, there were 271 controls and 198 cases.