Table 1.
ob genotype | % fat diet | Gender | n | Feed intake (g feed/g bw/day) | Feed intake (kcal AFE/g bw/day) | n | Water intake (mL/g bw/day) |
---|---|---|---|---|---|---|---|
wt/wt | 10 | F | 10 | 0.25 ± 0.04 | 0.90 ± 0.13 | 10 | 0.25 ± 0.05 |
M | 11 | 0.18 ± 0.05 | 0.65 ± 0.19 | 11 | 0.20 ± 0.04 | ||
| |||||||
ob/wt | 10 | F | 10 | 0.22 ± 0.03 | 0.82 ± 0.12 | 11 | 0.27 ± 0.06 |
M | 14 | 0.20 ± 0.05 | 0.72 ± 0.18 | 15 | 0.22 ± 0.06 | ||
| |||||||
ob/ob | 10 | F | 11 | 0.17 ± 0.04 | 0.62 ± 0.14 | 11 | 0.31 ± 0.16 |
M | 8 | 0.16 ± 0.02 | 0.59 ± 0.06 | 9 | 0.23 ± 0.10 | ||
| |||||||
wt/wt | 45 | F | 12 | 0.10 ± 0.02 | 0.44 ± 0.11 | 12 | 0.18 ± 0.04 |
M | 13 | 0.07 ± 0.03 | 0.30 ± 0.14 | 8 | 0.13 ± 0.04 | ||
| |||||||
ob/wt | 45 | F | 12 | 0.09 ± 0.03 | 0.41 ± 0.14 | 11 | 0.15 ± 0.05 |
M | 14 | 0.07 ± 0.03 | 0.30 ± 0.13 | 10 | 0.12 ± 0.02 | ||
| |||||||
ob/ob | 45 | F | 11 | 0.05 ± 0.02 | 0.25 ± 0.07 | 2 | 0.24 ± 0.08 |
M | 8 | 0.07 ± 0.02 | 0.31 ± 0.08 | 4 | 0.12 ± 0.01 |
Feed and water intake (mean ± SD) were recorded in some of the mice from each treatment group kept in metabolic cages for 24 h at age 9–11 weeks, after they were getting accustomed to the cages the day before. There were no consistent significant differences in feed and water intake between Apc Min/+ and Apc +/+ mice, or between 0.9% NaCl- or PhIP-treated mice, and therefore these data were pooled. F = females, M = males, and n = number of mice.