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. 2015 Aug 10;2015:675201. doi: 10.1155/2015/675201

Figure 3.

Figure 3

The effect of PEP on the histopathological structure of the pancreas in DM rats (H&E staining). A DM model was established by feeding rats a high-fat diet and injecting them with a low dose of STZ. After the model was established, PEP (0, 150, 300, and 600 mg/kg) was administered intragastrically as an intervention for 28 d (n = 10 rats). The pancreatic tissues were collected, embedded, sectioned, and stained with H&E. (a) control: control group; (b) model: model group; (c) metformin HC: metformin HC group; (d) 150 mg/kg: low-dose PEP group; (e) 300 mg/kg: medium-dose PEP group; (f) 600 mg/kg: high-dose PEP group.