Fig. S1.

Metabolic abnormalities in pol η^−/− mice. (A) Food and drinking water uptake of WT and pol η^−/− mice fed a normal chow diet (n = 12). (B) Fasting plasma glucose concentrations in 4- and 72-wk-old mice (n = 8). (C) Energy expenditure of WT and pol η^−/− mice (n = 12). (D) H&E staining of liver tissues from mice fed normal chow (4 and 72 wk of age). FFM, fat-free mass; w, week; The data, which are shown as the mean ± SEM, were analyzed by the Student t test (*P < 0.05 vs. the corresponding WT value).