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Model of SufB precursor processing under ROS/RNS stresses. We propose that the C+1 residue, crucial for splicing, also coordinates the [Fe-S] cluster of the active SufB protein. Under ROS/RNS stresses, the C+1 of the SufB precursor can either disulfide bond, resulting in precursor accumulation (PA), or become modified (star), leading to N-terminal cleavage (NC). See Discussion for detailed explanation.
