Table 2.

Zero substitution, $>$ 4× upregulated genes, ages

Gene	Exon bases	exon bases ($>$ 20×)	age (×${10}^6$ y)	${\text{log}}_2\left(\text{DR}/\text{WT}\right)$
PRDX4*	921	801	3,556.3	5.9
PGK1†	2,733	2,273	3,556.3	2.0
NOB1‡	1,775	1,535	2,269.5	5.9
CKS1B§	1,015	816	2,269.5	4.4

^*Spermatogenesis, oxidation−reduction process.

^†Gluconeogenesis, glycolysis, phosphorylation.

^‡Proteosome biogenesis.

^§Regulates MM growth.