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. 2015 Jul;3(7):e341–e422. doi: 10.1016/S2214-109X(15)00038-8

Table 3.

Association between maternal age and low birthweight, preterm birth, 2-year stunting and wasting, non-completion of secondary education, adult overweight or obesity, high blood pressure, and abnormal glucose tolerance

Low birthweight Preterm birth 2-year stunting 2-year wasting Non-completion of secondary schooling Adult overweight or obesity Adult high blood pressure Adult impaired fasting glucose or diabetes
Model 1—Maternal age (years; adjusted for sex only)
≤19 1·43 (1·26–1·62) 1·44 (1·21–1·72) 1·37 (1·20–1·56) 1·12 (0·86–1·46) 1·32 (1·15–1·51) 1·07 (0·92–1·25) 1·00 (0·87–1·16) 0·87 (0·64–1·18)
20–24 1·00 (Ref) 1·00 (Ref) 1·00 (Ref) 1·00 (Ref) 1·00 (Ref) 1·00 (Ref) 1·00 (Ref) 1·00 (Ref)
25–29 0·83 (0·75–0·92) 0·91 (0·78–1·06) 0·84 (0·76–0·93) 0·91 (0·75–1·11) 0·80 (0·72–0·90) 0·96 (0·84–1·08) 1·05 (0·94–1·19) 0·98 (0·78–1·23)
30–34 0·82 (0·72–0·93) 0·91 (0·77–1·08) 0·93 (0·83–1·04) 1·05 (0·84–1·31) 0·86 (0·76–0·98) 1·06 (0·92–1·21) 1·11 (0·97–1·27) 0·69 (0·52–0·91)
≥35 0·94 (0·81–1·08) 1·30 (1·08–1·57) 1·18 (1·03–1·35) 0·97 (0·74–1·28) 0·99 (0·85–1·16) 1·01 (0·86–1·19) 1·08 (0·92–1·26) 1·06 (0·79–1·41)
p* <0·0001 0·29 0·02 0·64 <0·0001 0·76 0·17 0·86
p <0·0001 <0·0001 <0·0001 0·16 <0·0001 0·74 0·35 0·29
Model 2 (adjusted for sex and socioeconomic factors)
≤19 1·36 (1·19–1·56) 1·35 (1·12–1·62) 1·23 (1·06–1·41) 1·05 (0·80–1·38) 1·13 (0·97–1·31) 1·11 (0·95–1·29) 1·00 (0·86–1·16) 0·87 (0·64–1·19)
20–24 1·00 (Ref) 1·00 (Ref) 1·00 (Ref) 1·00 (Ref) 1·00 (Ref) 1·00 (Ref) 1·00 (Ref) 1·00 (Ref)
25–29 0·87 (0·78–0·97) 0·91 (0·77–1·06) 0·88 (0·79–0·98) 0·95 (0·77–1·16) 0·87 (0·77–0·99) 0·95 (0·84–1·08) 1·04 (0·93–1·18) 0·98 (0·78–1·23)
30–34 0·83 (0·73–0·94) 0·92 (0·77–1·10) 0·87 (0·77–0·99) 0·98 (0·78–1·23) 0·87 (0·76–1·01) 1·05 (0·91–1·21) 1·10 (0·96–1·25) 0·69 (0·52–0·92)
≥35 0·92 (0·79–1·07) 1·28 (1·04–1·56) 0·97 (0·83–1·13) 0·79 (0·59–1·06) 0·88 (0·74–1·05) 1·02 (0·87–1·21) 1·06 (0·90–1·24) 1·05 (0·78–1·43)
p* <0·0001 0·69 0·0009 0·19 0·001 0·59 0·30 0·88
p <0·0001 <0·0001 0·003 0·92 0·10 0·56 0·35 0·22
Model 5 (adjusted for sex, socioeconomic factors, maternal height, breastfeeding duration, and parity)
≤19 1·18 (1·02–1·36) 1·26 (1·03–1·53) 1·46 (1·25–1·70) 1·11 (0·83–1·49) 1·38 (1·18–1·62) 1·10 (0·94–1·29) 0·95 (0·81–1·11) 0·87 (0·63–1·20)
20–24 1·00 (Ref) 1·00 (Ref) 1·009 (Ref) 1·00 (Ref) 1·00 (Ref) 1·00 (Ref) 1·00 (Ref) 1·00 (Ref)
25–29 0·96 (0·85–1·08) 0·96 (0·81–1·14) 0·72 (0·63–0·81) 0·84 (0·68–1·04) 0·71 (0·62–0·81) 0·98 (0·86–1·12) 1·07 (0·94–1·21) 0·98 (0·77–1·25)
30–34 0·94 (0·82–1·09) 0·96 (0·79–1·18) 0·63 (0·54–0·73) 0·82 (0·63–1·06) 0·63 (0·53–0·74) 1·12 (0·96–1·30) 1·13 (0·97–1·31) 0·69 (0·51–0·94)
≥35 1·03 (0·86–1·23) 1·33 (1·05–1·67) 0·64 (0·54–0·77) 0·66 (0·48–0·90) 0·59 (0·48–0·71) 1·13 (0·94–1·36) 1·08 (0·90–1·29) 1·03 (0·74–1·44)
p* 0·14 0·37 <0·0001 0·01 <0·0001 0·44 0·18 0·94
p 0·001 0·0005 <0·0001 0·32 0·0008 0·69 0·09 0·16

Data are odds ratio (95% CI).

*

p=p value for linear association.

p=p value for quadratic association. p values derived with logistic regression, with maternal age and maternal age2 as continuous variables and outcomes as binary.