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. 2015 Aug 24;5:13180. doi: 10.1038/srep13180

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(left) Distance analysis between Val131 (cytoplasmic side of TM3) and Leu222 (cytoplasmic side of TM5). (right) Superimposition of representative structure from MD (red) with crystal structure (green) near cytoplasmic side of TM5 and TM3. Distances between Val131 and Leu222 are 11.5 Å and 15.8 Å for crystal and representative structure, respectively. (bottom) Superimposition of representative structure from MD (red) with crystal structure (green) near EC side of TM6.