Table 1.
Characteristics of patients with rheumatoid arthritis included in the longitudinal cohorts studied. Age, symptom duration, TJC, SJC, CRP, ACPA and RF were assessed at baseline
| EAC Part 1 | EAC Part 2 (MRI) | Wichita | Umeå | Groningen | Lund | |
|---|---|---|---|---|---|---|
| Total number of patients | 698 | 56 | 293 | 459 | 278 | 147 |
| Total number of radiographs | 3.643 | 105 | 1.062 | 868 | 865 | 781 |
| Mean number of radiographs per patient (SD) | 5.2 (2.1) | 1.9 (0.3) | 3.6 (2.0) | 1.9 (0.3) | 3.1 (1.4) | 5.3 (0.8) |
| Year of diagnosis | 1993–2006 | 2010–2012 | 1963–1999 | 1995–2010 | 1945–2001 | 1985–1989 |
| Radiographic follow up in years | 7 | 1 | 15 | 2 | 14 | 5 |
| Method of scoring | SHS | SHS | SHS | Larsen | SHS | Larsen |
| Age, years | ||||||
| Mean (SD) | 56.6 (15.6) | 55.9 (14.2) | 48.8 (14.2) | 53.9 (14.5) | 49.3 (12.6) | 50.7 (11.5) |
| Median (IQR) | 58 (46–68) | 59 (46–65) | 49 (39–60) | 56 (45–64) | 50 (40–59) | 51 (43–59) |
| Range | 17.1–92.4 | 21.5–77.8 | 16.0–83.0 | 17.0–83.0 | 18.3–76.3 | 18.0–78.0 |
| Female sex (%) | 474 (67.8) | 31 (55.4) | 226 (77.1) | 321 (69.2) | 196 (70.5) | 98 (66.7) |
| Symptom duration in weeks (IQR) | 19 (11–37) | 18 (11–32) | NA | NA | NA | 43 (29–62) |
| TJC (IQR) | 8 (5.0–12.0) | 7 (4.0–10.5) | NA | NA | NA | NA |
| SJC (IQR) | 8 (4.0–14.0) | 5 (3.5–10.0) | NA | NA | NA | NA |
| ESR (IQR) | 33 (19–54) | 25 (10–41) | NA | NA | NA | NA |
| CRP (IQR) | 17 (8.0–40.0) | 11 (3.0–20.5) | NA | NA | NA | NA |
| ACPA positivity (%) | 365 (53.7) | 33 (63.5) | 238 (82.1) | 339 (73.1) | 162 (79.4) | 114 (80.3) |
| RF positivity (%) | 405 (58.2) | 36 (64.3) | NA | NA | 259 (93.8) | 115 (80.3) |
Age, symptom duration, TJC, SJC, ESR, CRP, ACPA and RF were assessed at baseline
EAC Early Arthritis Clinic, MRI magnetic resonance imaging, TJC tender joint count, SJC swollen joint count, CRP C-reactive protein, ESR erythrocyte sedimentation rate, ACPA anti-citrullinated peptide antibodies, RF rheumatoid factor, SHS Sharp-van der Heijde