Figure 2.

ABC expression in Barrett’s metaplasia: (A) Immunofluorescence microscopy for expression and localization of ABC protein in squamous esophageal mucosa (SQ) and nondysplastic Barrett’s metaplasia (BE). Arrowheads depict nuclear localization, whereas arrows show perinuclear cytoplasmic localization. Representative tissue staining of at least three different tissues is presented. (B) Western blot analysis of ABC protein expression in representative human esophageal biopsies. Significantly elevated amounts of ABC were demonstrated in Barrett’s metaplastic mucosa compared with the corresponding paired squamous mucosa.